منابع مشابه
Steroid Hormones and Ovarian Cancer
Globally, ovarian cancer is the 6th most common malignancy in developed countries, responsible for 100,300 new cases and 64,500 deaths annually (Jemal et al., 2011). Approximately 90% of ovarian cancers arise within the ovarian surface epithelium (OSE) or the fallopian tube surface epithelium; the remainder of ovarian malignancies develops from other ovarian tissues (sex cord-stromal, germ cell...
متن کاملNon-steroid Ovariak Hormones
In 1950, Frieden and Hisaw (2) described a method for the isolation of relaxin from the ovaries of pregnant sows. This method, which involved extraction of ground whole ovaries with 5 per cent aqueous SaCl, fractionation with ethanol, and finally precipitation with acetone, afforded good yields (200 to 250 GPU’ of relaxin per gm. of fresh tissue), and material of saCsfactory potency (30 to 90 G...
متن کامل//steroid Hormones and Regulation of Ovarian Function
A family of C29 4,4-dimethylsterol intermediates in the cholesterol biosynthetic pathway from lanosterol has been found to induce oocytes to resume meiosis.[248] One of these sterols, 4,4-dimethyl-5α-cholest-8,14,24-triene-3β-ol, was extracted from human follicular fluid and named follicular fluid meiosis–activating substance (FF-MAS). A related compound, 4,4-dimethyl-5α-cholest-8,24-diene-3β-o...
متن کاملSteroid Hormones: Membrane transporters of steroid hormones
The discovery of a plasma membrane ABC protein that exports steroids in yeast highlights the possibility that similar membrane sorting systems in mammalian cells may modulate the access of steroids to their receptors.
متن کاملNon-genomic actions of sex steroid hormones.
Steroid hormone receptors have been traditionally considered to act via the regulation of transcriptional processes, involving nuclear translocation and binding to specific response elements, and ultimately leading to regulation of gene expression. However, novel non-transcriptional mechanisms of signal transduction through steroid hormone receptors have been identified. These so-called 'non-ge...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1957
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)63663-x